Sensitive and specific clinically diagnosis of SARS-CoV-2 employing a novel biosensor based on boron nitride quantum dots/flower-like gold nanostructures signal amplification질화붕소 양자점/꽃모양 금 나노구조 신호 증폭 기반의 새로운 바이오센서를 이용한 SARS-CoV-2의 민감하고 구체적인 임상 진단Article Published on 2022-07-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification biosensor Boron boron nitride carbon characteristic clinical sample clinical samples clinical trials clinically comparable COVID-19 COVID-19 outbreak COVID-19 pandemic cross-reactivity cutoff value Detection limit Diagnosis diagnosis of SARS-CoV-2 DNA Effect electrochemical biosensor evaluate form gold group growth Health Health crisis IAV Influenza influenza A Mutation nucleic acid nucleic acid amplification Patient platform point-of-care positive quantitation Quantitative receiver operating characteristic receiver operating characteristic curve remained RNA RNA fragment RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Screen sensitive sensitivity significant difference specificity ssDNA statistical analysis t-test Virus diagnosis. was tested [DOI] 10.1016/j.bios.2022.114209 PMC 바로가기 [Article Type] Article
Prognostic accuracy of inflammatory markers in predicting risk of ICU admission for COVID-19: application of time-dependent receiver operating characteristic curvesCOVID-19에 대한 ICU 입원 위험 예측에서 염증 표지자의 예후 정확도: 시간 종속 수신기 작동 특성 곡선의 적용Observational Study Published on 2022-06-012022-09-11 Journal: The Journal of international medical research [Category] MERS, 바이오마커, 임상, [키워드] 95% CI 95% confidence interval Accuracy Admission approach Ayatollah baseline level baseline levels C-reactive protein C-reactive protein (CRP Care characteristic COVID-19 COVID-19 infection CRP cutoff value evaluate evaluated greater hazard ratio Hospital admission Hospitalization ICU ICU admission Inflammatory marker inflammatory markers intensive care intensive care unit intensive care unit admission Iran lymphocyte Medical Sciences neutrophil Neutrophil-to-lymphocyte ratio NLR observational study occur outcome Patient patients with COVID-19 predictor reached receive receiver operating characteristic receiver operating characteristic curve referred to risk ROC ROC Curve ROC curves severe COVID-19 Severe COVID-19 Infection significantly Stratification time-dependent area under the receiver operating characteristic curve. time-dependent ROC curve university [DOI] 10.1177/03000605221102217 PMC 바로가기 [Article Type] Observational Study
A novel epidemiological scoring system for the prediction of mortality in COVID-19 patientsCOVID-19 환자의 사망률 예측을 위한 새로운 역학 채점 시스템Article Published on 2022-05-022022-09-11 Journal: Transactions of the Royal Society of Tropical Medi [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Admission age AUROC breathlessness characteristic clinical symptom Clinical symptoms co-morbidities Cohort Comorbidities Comorbidity coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patient COVID-19 patients COVID-19 scoring system CSS develop diabete diabetes diagnostic Diagnostic accuracy early prediction of mortality early stage epidemiological group higher risk hospital independent risk factor indicate inflammatory markers Mann Whitney U Test medium morbidities Mortality MOST patient age positive positive relationship predicted proportion receiver operating characteristic receiver operating characteristic curve reported risk Risk factors Risk factors. Scoring Scoring and validation cohort scoring system Sensitivity and specificity severe COVID-19 patients Treatment Triage validation cohort were used [DOI] 10.1093/trstmh/trab108 PMC 바로가기 [Article Type] Article
Hair cortisol change at COVID-19 pandemic onset predicts burnout among health personnelCOVID-19 전염병 발병 시 모발 코르티솔 변화는 의료진의 피로를 예측합니다Article Published on 2022-04-012022-09-11 Journal: Psychoneuroendocrinology [Category] 바이오마커, [키워드] Adding Anxiety association biological marker Burnout Canada change characteristic cortisol COVID-19 COVID-19 pandemic Depression disorder expected Factor Factors hair Health Health personnel Healthcare systems healthcare worker Healthcare workers individual IQR logistic regression model median mental health multivariable regression model multivariable regression models Non-invasive outcome pandemic participant Post-traumatic stress disorder Post-traumatic stress disorder. predict predicted Prevalence Prevent provided Psychological distress psychological health Quebec, Canada receiver operating characteristic receiver operating characteristic curve Research risk factor secretion Stress stress response Symptoms variable while [DOI] 10.1016/j.psyneuen.2021.105645 PMC 바로가기 [Article Type] Article
Antiviral metabolite 3′-deoxy-3′,4′-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19항바이러스 대사 산물 3'-deoxy-3',4'-didehydro-cytidine은 혈청에서 검출 가능하며 COVID-19를 포함한 급성 바이러스 감염 식별Article Published on 2022-03-112022-09-11 Journal: Med (New York, N.Y.) [Category] MERS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] 95% CI acute infection acute viral infection Admission an area Antiviral AUC Bacterial Bacterial infection Bacterial infections Biomarker characteristic CMPK2 Cohort correlated COVID-19 Critical cytidine ddhC detectable Diagnosis diagnostic diagnostics emergency department enzyme Enzymes examined FIVE Gene Expression healthy controls High-resolution highlight identify implicated in viral in vivo independent inflammatory conditions interferon Liquid chromatography management marker mass spectrometry metabolite metabolome metabolomics NIHR pandemic Patient precursor Profiling receiver operating characteristic receiver operating characteristic curve responsible sera serum significantly small molecule Support transcripts validation cohort viperin Viral viral infection viral infections viral. [DOI] 10.1016/j.medj.2022.01.009 PMC 바로가기 [Article Type] Article
The Use of Wearable Pulse Oximeters in the Prompt Detection of Hypoxemia and During Movement: Diagnostic Accuracy Study저산소혈증의 즉각적인 감지 및 운동 중 착용형 맥박산소 측정기의 사용: 진단 정확도 연구Original Paper Published on 2022-02-152022-09-10 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] Accuracy adjusted analyzed arterial blood arterial blood oxygen saturation blood oxygen Blood oxygen saturation calculate Care characteristic Clinical deterioration clinical setting comparable continuous monitoring COVID-19 disease detect detection Deterioration Diagnostic accuracy disease estimate evaluated hospital Hypoxemia hypoxia Identifier Isolation ISRCTN registry mHealth motion objective organization oximeter oxygen oxygen saturation Participants Patient patient monitoring patients with COVID-19 performance peripheral peripheral oxygen saturation Philip physiological pulse Pulse oximeter Pulse Oximeters receiver operating characteristic receiver operating characteristic curve receiving Registration reliability report required Result risk root rubbing sensitivity specificity Support Tablet Tapping was used Wavelet wearable pulse oximeter wearable technology [DOI] 10.2196/28890 PMC 바로가기 [Article Type] Original Paper
Differential Dynamics of SARS-CoV-2 Binding and Functional Antibodies upon BNT162b2 Vaccine: A 6-Month Follow-UpBNT162B2 백신에 대한 SARS-COV-2 결합 및 기능적 항체의 차등 역학 : 6 개월 추적 관찰Article Published on 2022-02-022022-09-01 Journal: Viruses [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, [키워드] anti-RBD Anti-RBD IgG anti-Spike IgG antibody association binding BNT162b2 characteristic collected comparable correlates of protection COVID-19 cutoff point decrease Definition demonstrated dose Dynamics functional high correlation Humoral response IgG indications Laboratory laboratory procedures lack less maturation mRNA NAb NAbs Neutralizing antibodies neutralizing antibody of BNT162b2 receiver operating characteristic receiver operating characteristic curve receiving resulting SARS-CoV-2 serum sample serum samples vaccination were measured WHO [DOI] 10.3390/v14020312 PMC 바로가기 [Article Type] Article
An automated chemiluminescent immunoassay (CLIA) detects SARS-CoV-2 neutralizing antibody levels in COVID-19 patients and vaccinees자동화된 화학발광 면역분석(CLIA)은 COVID-19 환자와 백신 수혜자의 SARS-CoV-2 중화 항체 수준을 감지합니다.Article Published on 2022-02-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Analysing Antigen antigens automated can be used characteristic chemiluminescent immunoassay CLIA Concentration concentrations convalescent patient Coronavirus-2 COVID-19 patient cut-off value detect Diagnosis domain ectodomain Effectiveness evaluate evaluated groups half-life healthy individual indicated Infection linear mathematical mathematical model Mathematical models Microneutralization test MNT NAb titer NAb titers neutralizing antibody positive Protective protocol R 2 RBD receiver operating characteristic receiver operating characteristic curve respiratory SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 vaccine SARS-CoV-2 vaccine. sensitivity severe acute respiratory syndrome Coronavirus specificity tested Treatment Vaccine vaccinee vaccinees variable [DOI] 10.1016/j.ijid.2021.12.316 PMC 바로가기 [Article Type] Article
A Model Predicting Mortality of Hospitalized Covid-19 Patients Four Days After Admission: Development, Internal and Temporal-External Validation입원 4일 후 입원한 Covid-19 환자의 사망률을 예측하는 모델: 개발, 내부 및 시간-외부 검증Cellular and Infection Microbiology Published on 2022-01-242022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 변종, [키워드] Admission age Alpha Alpha variant AUROC B.1.1.7 blood parameter C-reactive protein calibration slope Care characteristic clinical coronavirus COVID-19 creatinine cross Day develop development discharge explained Fever Final FIVE haematological parameter haematological parameters Health Health care Health care system Hospitalized hospitalized COVID-19 patients hospitalized patients hospitals Identifier in-hospital mortality internal Lactate lactate dehydrogenase linear mixed model Logistic regression Model Mortality mutations non-survivor Non-survivors objective Occurrence on admission parameter Patient Platelet Platelet count Prediction model prevalent prognostic model receiver operating characteristic receiver operating characteristic curve reduce Registration Result slope Support supported survival survivor validation variable variable selection variables Variation was done [DOI] 10.3389/fcimb.2021.795026 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
High-sensitivity troponin in the prognosis of patients hospitalized in intensive care for COVID-19: a Latin American longitudinal cohort studyCOVID-19로 중환자실에 입원한 환자의 예후에서 고감도 트로포닌: 라틴 아메리카 종단 코호트 연구Article Published on 2022-01-012022-09-11 Journal: Revista Brasileira de Terapia Intensiva [Category] 바이오마커, [키워드] an area area under the curve association Chain Reaction Cohort cohort of patient confidence interval Confidence intervals COVID-19 COVID-19 diagnosis COVID-19 patient Cox proportional hazard Cox proportional hazards model death demonstrated English hazard ratio hazard ratios Hospitalized indicate intensive care Latin longitudinal cohort study Mortality mortality rate multivariate model Non-survivors p value pacientes com COVID-19 Patient polymerase chain polymerase chain reaction positive predict Prevalence prognosis of patient Prognostic marker proportional hazards model prospectivo receiver receiver operating characteristic receiver operating characteristic curve single-center study sob survivor troponin was performed [DOI] 10.5935/0103-507X.20220006-pt PMC 바로가기 [Article Type] Article